Metabolic Changes in Human Brain Evolution and Schizophrenia

Earlier this year, researchers at the Max Plank Institute for Evolutionary Anthropology, the Shanghai branch of the Chinese Academy of Sciences and Cambridge University published a study in the journal Genome Biology providing further evidence that the evolution of human cognitive abilities was accompanied by adaptive changes in brain metabolism, potentially pushing the human brain to the limit of its metabolic capabilities [1]. The results support the theory that schizophrenia is a consequence of human brain evolution.

Mapping Connections in the Human Brain

The first high-resolution structural connection map of the human cerebral cortex was published earlier this month in the journal PLoS Biology. The study reveals regions that are highly connected and central, forming a structural core network [1]. Intriguingly, this core network consists of many areas that are more active when we’re at rest than when we’re engaged in a task that requires concentration.