Discover the Science of Health
There are a multitude of alternative sweeteners available on the market today. Some of these, like fructose, contain calories. Others — the so-called non-nutritive sweeteners — do not. While these “artificial” sugars don’t elevate blood glucose like table sugar does (which makes them more appropriate and healthy for diabetics than traditional sugar is), and while the body can’t convert them into fat, they’re not completely free of problems and complications as components of diet.
Biomarker Bulletin is an occasionally recurring update of news focused on biomarkers aggregated at BiomarkerCommons.org. Biomarkers are physical, functional or biochemical indicators of normal physiological or disease processes. The individualization of disease management — personalized medicine — is dependent on developing biomarkers that promote specific clinical domains, including early detection, risk, diagnosis, prognosis and predicted response to therapy.
A satellite symposium, Recent Advances in Biomarker Discovery for Parkinson’s Disease, is being sponsored by Covance on November 13th, 2011 at the Society for Neuroscience Annual Meeting in Washington, D.C.
The New York Academy of Sciences (NYAS) will be holding an afternoon event in January 2012 that focuses on biomarkers and brain imaging of presymptomatic Alzheimer’s disease.
Earlier this month, the National Institutes of Health announced that the National Institute of Dental and Craniofacial Research (NIDCR) Institute will support mission-relevant investigator-initiated Phase I, II, III or IV clinical trial cooperative agreement applications or biomarker evaluation studies that require prospective collection of clinical outcomes and clinical specimens.
The National Institutes of Health announced Thursday that the Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) will support studies that propose adapting adult biomarkers to children.
CLC bio is participating in a $4 million Danish collaboration focused on the identification and validation of biomarkers of prostate cancer risk and aggressiveness.
Popular hydration options among runners and endurance athletes include water and carbohydrate-electrolyte solutions, also known as sports drinks. Sports drink manufacturers, in an effort to sell more product, have convinced a large number of athletes — including accomplished runners — that the key to avoiding medical problems during exercise and racing is to drink as much as possible.
According to new research published in the British Journal of Sports Medicine [1], many runners have erroneous beliefs about their hydration needs, and thus overhydrate by drinking according to a schedule, or drinking “as much as possible.” This increases the risk of exercise-associated hyponatremia, an electrolyte disturbance in which the sodium concentration in the serum is lower than normal. Hyponatremia can cause nausea and vomiting, headache, confusion, fatigue, muscle weakness, cramps, seizures, decreased consciousness and/or coma. With events from community 10K races all the way up to marathons and ultramarathons increasing in popularity among non-elite athletes, understanding public belief about hydration and subsequent hydration behavior is an important public health topic.
The 2011 Nobel Prize in Physiology or Medicine was announced on Monday. The prize was awarded to three scientists for their work on the body’s immune system.
The prize of 10-million-Swedish-krona (US$1.5-million) was divided, one half jointly to Bruce A. Beutler, age 54, at The Scripps Research Institute, La Jolla, California, and Jules A. Hoffmann, age 70, at the French National Centre for Scientific Research (CNRS) Institute of Cell and Molecular Biology in Strasbourg, for their discovery of receptor proteins that can recognize bacteria and other microorganisms and activate innate immunity, and the other half to Ralph M. Steinman, age 68, at Rockefeller University in New York, for his discovery of dendritic cells of the immune system and their unique capacity to activate and regulate adaptive immunity, the later stage of the immune response during which microorganisms are cleared from the body.
The National Institutes of Health recently announced that it is awarding $143.8 million to challenge the status quo with innovative ideas that have the potential to propel fields forward and speed the translation of research into improved health for the American public.
These awards are granted under three innovative research programs supported by the NIH Common Fund: the NIH Director’s Pioneer, New Innovator, and Transformative Research Projects Awards. The Common Fund, enacted into law by Congress through the 2006 NIH Reform Act, supports trans-NIH programs with a particular emphasis on innovation and risk taking.
