Alzheimer’s Disease May Protect Against Cancer and Vice Versa

ResearchBlogging.org

As we get older, and care for our parents as they get older, the most feared age-related conditions we face are arguably Alzheimer’s disease and cancer. But researchers at Washington University have just shown that at least we don’t have to fear both of them at the same time; they recently published a paper in the medical journal of the American Academy of Neurology demonstrating that people with Alzheimer’s disease have a significantly reduced risk of being hospitalized for cancer [1].

Feared age-related conditions

This potential link between these two diseases had been noted for some time, but in this study researchers devoted considerable effort to overcoming the limitations in their previous work. Firstly, they used a population-based sample of 3,020 people older than 65, so their results were not limited to a particular geographic area or socio-economic segment of society. Secondly, they used hospital records rather than informant reports to quantify cancer diagnoses. This controlled for the risk that people with Alzheimer’s disease may be less likely to report their cancers than those without. And lastly, to ensure that they were not seeing less cancer in Alzheimer’s patients because physicians were less likely to look for cancer in people with dementia, or because people with dementia simply die earlier than those without it and thereby avoid cancer, they also looked at cancer risk among people with vascular dementia. Vascular dementia is not neurodegenerative in origin; rather, it results from brain damage due to vascular pathology.

Drug for Multiple Myeloma Demonstrated to Significantly Extend Disease-Free Survival

Initial results from a large, randomized clinical trial for patients with multiple myeloma, a cancer of the blood and bone marrow, showed that patients who received the oral drug lenalidomide (Revlimid, also known as CC-5013) following a blood stem cell transplant had their cancer kept in check longer than patients who received a placebo. The clinical trial, for patients ages 18 to 70, was sponsored by the National Cancer Institute (NCI), and conducted by a network of researchers led by the Cancer and Leukemia Group B (CALGB) in collaboration with the Eastern Cooperative Oncology Group (ECOG) and the Blood and Marrow Transplant Clinical Trials Network (BMT CTN). The BMT CTN is co-sponsored by NCI and the National Heart, Lung, and Blood Institute, both parts of the National Institutes of Health.

You Can Help Improve the Health of America: Healthy People 2020

The U.S. Department of Health and Human Services (HHS) is inviting people to submit comments and suggestions as part of the collaborative process for Healthy People 2020. Healthy People is consortium of diverse, motivated and dedicated agencies and organizations committed to working together to help achieve health goals and objectives for the nation. As a national initiative, Healthy People 2020’s success depends on public input.

Healthy People 2020

Every 10 years, the HHS leverages scientific insights and lessons learned from the past decade, along with knowledge of new and emerging issues, data, trends and innovations to set the nation’s health priorities. In 2007 and 2008, the Healthy People 2020 framework was established, consisting of the vision, mission and overarching goals. In 2009, specific objectives and strategies to achieve them were developed. This month, the HHS is requesting public comments on the draft set of proposed objectives for Healthy People 2020. You are invited to comment on the proposed objectives and topic areas and suggest additional objectives and/or topic areas that you feel are missing.

Chromosome Telomeres and the Nobel Prize for Medicine

nobel medal in medicineThe 2009 Nobel Prize in Physiology or Medicine was announced earlier this week. The prize was awarded to three U.S. scientists for the discovery of how chromosomes are protected by telomeres and the enzyme telomerase.

Two women, Elizabeth H. Blackburn, age 61, at the University of California in San Francisco, and Carol W. Greider, age 48, at Johns Hopkins University School of Medicine in Baltimore along with one man, Jack W. Szostak, age 57, at Harvard Medical School, will share the $1.4 million prize.

The Review Is In: Lifestyle Changes Prevent Breast Cancer

This article was written by Allison Bland.

Experts agree that diet and nutrition can reduce risk of many diseases, including different types of cancer and chronic disease. A recent update to a 2007 report by the American Institute for Cancer Research/World Cancer Research Fund (AICR/WCRF) concludes that breast cancer deaths can be prevented by physical activity, breast feeding, a healthy diet and other preventative measures. The study is an update to the breast cancer chapter of Food, Nutrition, Physical Activity and the Prevention of Cancer: a Global Perspective [1]. Earlier conclusions were based on data from 873 studies evaluating the relationship between diet, physical activity, obesity and cancer [2]. The 2009 update includes evidence from an additional 81 studies.