Rehabilitation After Stroke: They do it with Mirrors

Recent research by Michielsen and colleagues has demonstrated that “mirror therapy”, which can be given at home, results in significant, albeit modest, improvement in arm, wrist and hand movement abilities of stroke patients [1]. Mirror therapy is where the arm with impaired movement is placed behind a mirror and the unimpaired arm is reflected in the mirror, giving the appearance to the patient that when the unimpaired arm is moved, the impaired arm is also moving.

Mirror therapy for stroke rehabilitation

Book Review: The SharpBrains Guide to Brain Fitness

Many people believe that the brain is hardwired in childhood and, as we grow older, cognitive decline is inevitable; we becoming more forgetful, less inclined to seek new experiences and more set in our ways. During the late 1990s, the work of early childhood advocates to focus on learning during the first three years of life had a dramatic impact public opinion and social policy that has lasted almost a decade. Indeed, the importance of learning during a child’s first three years of life was widely accepted as a fact of early neurological development. Unfortunately, advocacy efforts actually countered what neuroscientists were discovering about the brain and its development [1].

Scientific research in the late 1990s was finding that the adult brain had a much greater capacity for neuroplasticity — the ability to change structure and function in response to thought, learning and experience — than was previously believed [2-3]. Neuroscientists found that the adult brain was capable of growing new dendrites, branched projections from a neuron or nerve cell that conduct electrochemical stimulation received from other neural cells toward the cell body of the neuron, which are often damaged as a result of traumatic head injury or stroke. In adult macaques, researchers found that new neurons were produced in brain regions important for congitive function [4]. The view that aging was equivalent to ubiquitous and rapid cognitive decline thus gave way to a recognition that, for some people, mental acuity continues well into old age. Today, it’s common to hear about “brain fitness” and/or “brain training” products that can help to maintain and/or rebuild cognitive performance. However, in this rapidly evolving field, it’s difficult to discern fact from fiction.

Neurodegenerative Disease and the Coming Epidemic

At Neuroscience 2008, the 38th annual meeting of the Society for Neuroscience held last month in Washington D.C., a number of researchers presented evidence that a small, soluble, clustered form of a protein called amyloid beta may be responsible for brain damage in Alzheimer’s disease patients [1]. In addition, scientists report that they are finding new sources and uses of neural stem cells that may replace cells damaged by neurodegenerative disorders such as Alzheimer’s and Parkinson’s disease [2].

neuronal-network.jpg
Creative Commons License photo credit: neurollero

Why are these reports significant? Because until recently, large insoluble amyloid beta plaques, or deposits, were considered the likely cause of Alzheimer’s disease. The plaques were thought to disrupt brain cell communication. However, new findings show that an early (i.e. small), soluble, clustered form of amyloid beta called protofibrils is found in high levels in the brains of people with Alzheimer’s disease [1]. Researchers also found a strong correlation between the presence of high levels of protofibrils in the brains of transgenic mouse models of Alzheimer’s disease and the cognitive impairments associated with the disease.

Health Highlights – September 10th, 2007

Health Highlights is a biweekly summary of particularly interesting articles from credible sources of health and medical information that we follow & read. For a complete list of recommeded sources, see our links page.

Health Highlights
  • The Business of Bottled Water | Think Bigg

    Because bottle water is considered a food, it’s regulated by the FDA. In contrast, tap water is regulated by the EPA. A Natural Resources Defense Council study found that bottled water sold in the U.S. isn’t necessarily cleaner or safer than most tap water. Tabetha at Think Bigg writes a thought-provoking article on the business of bottled water.

  • DNA and Spit Law Enforcement Campaigns | Eye on DNA

    What is it with people spitting at other people? Hsien at Eye on DNA tells us about the spit law enforcement campaign in England. Maybe that’ll make them think twice about spitting!

  • I Could Swear I’ve Read This Post Before | Healthbolt

    New clues regarding deja vu have Sara at Healthbolt saying “I could swear I’ve read this post before.”

  • The Sherpa Silenced | Gene Sherpas: Personalized Medicine and You

    Steve Murphy, a.k.a. the Gene Sherpa, is making an appeal for more Gene Sherpas:

    I am now putting out a plea to all of those who wish to harness genetics for health and longevity, those who wish to have science behind their clinical decision making, those who have a keen business sense and the ethics to make you shudder when you see what is being sold, those who wish to learn more about the future of genetic and medicine.

  • Chocolate Myths | Sciencebase

    David at Sciencebase writes about chocolate and the alkaloids caffeine and theobromine, and also provides a great example of unfounded claims and the importance of scientific evidence and source referencing.