Archives for December 2011

Microneedle Biosensors for Real-time Monitoring Of Body Chemistry

Scientists from North Carolina State University, Sandia National Laboratories, and the University of California, San Diego have developed new technology that enables doctors to detect real-time chemical changes in the body and to do so continuously for an extended period of time.

Scanning electron micrograph of a microneedle

Microneedles are very small needles in which at least one dimension –- such as length –- is less than one millimeter. Existing technology depends on taking samples and testing them; microneedle biosensors instead allow for continuous monitoring in real time.

Dr. Roger Narayan, professor in the joint biomedical engineering department of NC State’s College of Engineering and the University of North Carolina at Chapel Hill, explains:

We’ve loaded the hollow channels within microneedles with electrochemical sensors that can be used to detect specific molecules or pH levels. The idea is that customized microneedle sensor arrays could be developed and incorporated into wearable devices, such as something like a wristwatch, to help answer specific medical or research questions. For example, it could monitor glucose levels in a diabetic patient

The sensors are currently designed to detect glucose, pH levels and lactate. The research was recently published online in the journal Talanta.

Study: Multiplexed Microneedle-based Biosensor Array for Characterization of Metabolic Acidosis

Source: North Carolina State University News

Neti Pot Deaths Spark Tap Water Warnings

Sinus irrigation — the use of a saltwater solution to “wash” the sinuses — is recommended by allergists and other physicians as a mechanism for reducing symptoms of seasonal cold, allergies, and nasal or sinus irritation [1]. Research also suggests that sinus irrigation, generally performed at home using a special sinus irrigation bottle or a device called a neti pot, is safe and isn’t associated with any serious adverse effects [2].

Woman using a neti pot

Medical Mobile Video App Ringadoc

Ringadoc, a startup based in West Hollywood, California, has developed a new method for healthcare delivery. Their goal is to make healthcare instantly available to those in need. This is done by connecting patients to doctors for medical consultations over any phone, from any location, with complete audio and video conferencing.

Ringadoc

Chewing Gum Reduces Risk of Ear Infection in Children

Xylitol, or birch sugar, is a sugar naturally found in plums, strawberries, raspberries, and rowan berries. It is often used to sweeten toothpaste and chewing gum since it is as sweet as sucrose but does not cause tooth decay; this is because it cannot be fermented by bacteria that live in our mouths, and instead inhibits their growth. As the key step causing acute ear infections is the colonization of the middle ear by bacteria that move there from the mouth, researchers have hypothesized that xylitol might help prevent acute ear infections as well as tooth decay.

Researchers at the University of Toronto recently performed a meta-analysis of three Finnish studies and found that children who chewed gum — or took other products laden with xylitol, including lozenges or syrup — had about a 25% lower risk of developing an ear infection compared to controls. The study is published in the Cochrane Database of Systematic Reviews [1].

Child ear examination

Bone Marrow Donation Less Painful, Potentially Profitable

The National Marrow Donation Program (NMDP), which maintains the “Be The Match” registry to help provide individuals who would benefit from bone marrow donation with potential donors, is currently at odds with a ruling made by the Ninth Circuit Court in California. The court ruled that, while it’s not legal to compensate organ donors in the United States for their donation, one of the bone marrow-donating procedures isn’t “technically” organ donation — it’s blood donation — and donors can therefore be compensated.

Bone marrow harvest