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Heart Conditions Don’t Just Affect Older Adults

by on Friday, February 3, 2012

This article was written by Julianne Wyrick.

February is American Heart Month. Sponsored by the American Heart Association, American Heart Month is a time to battle cardiovascular disease and educate people on what they can do to live heart-healthy lives. Heart disease, including stroke, is the leading cause of death for men and women in the United States.

How much do you know about the condition of your heart? Heart health awareness typically focuses on heart disease in older adults caused by an unhealthy diet and a lack of exercise. But what if you could be at risk for cardiac arrest and sudden death even though you are young and in shape?

Heart arrhythmiaImage credit: Heart arrhythmia via Shutterstock

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Scientists Correct Sickle Cell Disease in Adult Mice

by on Tuesday, November 8, 2011

National Institutes of Health (NIH)-funded scientists have corrected sickle cell disease in adult laboratory mice by activating production of a special blood component normally produced before, but not after, birth.

Sickle cell disease is a recessive genetic disorder caused by a single base mutation in the gene for hemoglobin, beta locus (HBB). Hemoglobin is responsible for transporting oxygen throughout the body. People living with sickle cell disease have two copies of an altered gene that produces sickle hemoglobin instead of normal adult hemoglobin. Sickle hemoglobin changes shape after releasing its oxygen, causing the red blood cell to become stiff, misshapen and sticky, and slowing blood flow to tissues. This process damages organs and causes pain.

Normal hemoglobin vs sickle cell

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Sun Exposure, Vitamin D Can Affect Breakdown of Medicines

by on Monday, May 2, 2011

Genetic variation has been though to be responsible for the differences between people to metabolize certain drugs. The results of a recent study from the Karolinska Institutet in Sweden suggest that it may be even more complicated. Swedish reserchers have found that the body’s ability to break down medicines may be closely related to sunlight exposure and vitamin D, and thus may vary with the seasons. The study, published in the journal Drug Metabolism & Disposition, offers a completely new model to explain individual differences in the effects of drugs [1].

Sunlight can influence the breakdown of medicines in the body

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Genetic Risk Factor for Peanut Allergies Identified

by on Tuesday, April 26, 2011

It is difficult to find a school, camp or other facility catering to children these days that is not nut free. The prevalence of peanut allergies in preschool and school age children in the UK, the US and Canada is between 1.2 – 1.6%, which is about twice the rate at which it occurs in adults in these countries. Nut allergies, especially peanut allergies, are scary. And although they have been on the rise, no one really knows why. Researchers in Scotland recently reported in The Journal of Allergy and Clinical Immunology that mutations in the gene for filaggrin, a protein found in skin, are a “significant risk factor for peanut allergy” [1].

Peanuts and peanut butter

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1000 Genomes Project Publishes Analysis of Completed Pilot Phase

by on Wednesday, November 17, 2010

Small genetic differences between individuals help explain why some people have a higher risk than others for developing illnesses such as diabetes or cancer. Recently in the journal Nature, the 1000 Genomes Project, an international public-private consortium, published the most comprehensive map of these genetic differences, called variations, estimated to contain approximately 95 percent of the genetic variation of any person on Earth.

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