The Benefits of Animal Research

This article was written by Liz Hodge.

Most of us like a great steak, but may not want to think about how it arrives on our plate. Similarly, we want medicines, vaccines, antibiotics, surgery and diagnostic tools when we’re sick, but we may not care to know how exactly these treatments make it into our hospitals and pharmacies. Well, chances are, scientists developed them with the help of laboratory animals. Nearly every medical breakthrough involves animal research. From antibiotics to blood transfusions, dialysis to organ transplantation, vaccinations to chemotherapy, bypass surgery and joint replacement, practically every drug, treatment, medical device, diagnostic tool or cure we have today was developed with the help of laboratory animals. Each day, dedicated scientists study animals to find new cures for diseases and conditions that are currently incurable.

Animal research

The Cancer Genome Atlas Reports Molecular Characterization of Brain Tumors

A large-scale, multi-dimensional analysis of the genomic characteristics of glioblastoma, the most common primary brain tumor in adults, provides new insights into the roles of several genes and defines core biological pathways altered in tumor development [1]. The new Cancer Genome Atlas study, published in the September 4th advanced online edition of the journal Nature, also reveals a link between the DNA repair enzyme MGMT and a hypermutation phenotype, and has potential implications for the diagnosis and treatment of glioblastoma.

Glioblastoma is the most common and aggressive type of brain cancer. Patients newly diagnosed with glioblastoma have a median survival of approximately one year with generally poor response to therapy [2]. Gene expression profiling studies suggest multiple subtypes of glioblastoma that, when fully defined, may allow for more personalized therapeutic approaches [3-4].