Improving Mothers’ Literacy Skills May Be Best Way to Boost Children’s Achievement

Researchers funded by the National Institutes of Health concluded that programs to boost the academic achievement of children from low income neighborhoods might be more successful if they also provided adult literacy education to parents.

The researchers based this conclusion on their finding that a mother’s reading skill is the greatest determinant of her children’s future academic success, outweighing other factors, such as neighborhood and family income.

The analysis, performed by Narayan Sastry, Ph.D., of the University of Michigan, and Anne R. Pebley, Ph.D., of the University of California, Los Angeles, examined data on more than 3,000 families.

The study, appearing in Demography, was supported by NIH’s Eunice Kennedy Shriver National Institute of Child Health and Human Development.

Addition of Immunotherapy Boosts Pediatric Cancer Survival

Administering a new form of immunotherapy to children with neuroblastoma, a nervous system cancer, increased the percentage of those who were alive and free of disease progression after two years. The percentage rose from 46 percent for children receiving a standard therapy to 66 percent for children receiving immunotherapy plus standard therapy, according to the study in the Sept. 30, 2010, New England Journal of Medicine. The randomized phase III clinical trial was coordinated by the Children’s Oncology Group (COG), a national consortium of researchers supported by the National Cancer Institute (NCI), part of the NIH.

Lifestyle Intervention Improves Risk Factors in Type 2 Diabetes

An intensive lifestyle intervention program designed to achieve and maintain weight loss improves diabetes control and cardiovascular disease risk factors in overweight and obese individuals with type 2 diabetes, according to four-year results of the Look AHEAD study, funded by the National Institutes of Health and the Centers for Disease Control and Prevention. The results are published in the Sept. 27, 2010, issue of the Archives of Internal Medicine.

Depression High Among Youth Victims of School Cyber Bullying, NIH Researchers Report

Unlike traditional forms of bullying, youth who are the targets of cyber bullying at school are at greater risk for depression than are the youth who bully them, according to a survey conducted by researchers at the National Institutes of Health.

The new finding is in contrast to earlier studies of traditional bullying, which found that the highest depression scores were reported by another category of youth involved in bullying-bully victims. Past studies on traditional bullying show that bully-victims — those who both bully others and are bullied themselves — are more likely to report feelings of depression than are other groups.

Traditional forms of bullying involve physical violence, verbal taunts, or social exclusion. Cyber bullying, or electronic aggression, involves aggressive behaviors communicated over a computer or a cell phone.

NIH Expands Network Focused On How Genes Affect Drug Responses

The National Institutes of Health plans to spend $161.3 million over the next five years to expand the Pharmacogenomics Research Network (PGRN), a nationwide collaborative of scientists focused on understanding how genes affect a person’s response to medicines.

“Thanks to breakthroughs in genome sequencing technologies and our growing understanding of genetic variation among individuals, there has never been a better time to propel the field of pharmacogenomics,” said NIH Director Francis S. Collins, M.D., Ph.D. “Through these studies, we are moving closer to the goal of using genetic information to help prescribe the safest, most effective medicine for each patient.”