Archives for January 2010

NIH and D.C. Department of Health Team up to Combat District’s HIV/AIDS Epidemic

Officials from the National Institutes of Health and the city of Washington, D.C. today announced the new D.C. Partnership for HIV/AIDS Progress, a collaborative research initiative between NIH and the D.C. Department of Health designed to decrease the rate of new HIV infections in the city, improve the health of district residents living with HIV infection, and strengthen the city’s response to the HIV/AIDS epidemic. The partnership is being co-led by the National Institute of Allergy and Infectious Diseases (NIAID), part of NIH, and the D.C. Department of Health.

Gene Mutations Reveal Potential New Targets for Treating a Type of Non-Hodgkin’s Lymphoma

Researchers have discovered genetic mutations that may contribute to the development of an aggressive form of non-Hodgkin’s lymphoma. These findings provide insight into a mechanism that cancer cells may use to survive, thus identifying potential new targets for treatment of the disease. The study conducted by researchers at the National Cancer Institute (NCI), the National Institute for Allergy and Infectious Diseases, and the National Human Genome Research Institute, components of the National Institutes of Health, and colleagues appeared Jan. 7, 2010, in Nature.

Molecule Repairs Alcohol Metabolism Enzyme

An experimental compound repaired a defective alcohol metabolism enzyme that affects an estimated 1 billion people worldwide, according to research supported by the National Institute on Alcohol Abuse and Alcoholism (NIAAA). The findings, published Jan. 10, 2010 in the advance online edition of Nature Structural and Molecular Biology, suggest the possibility of a treatment to reduce the health problems associated with the enzyme defect.

NIH Awards $18.3 Million in Recovery Act Funds to Support Science, Technology, Engineering and Mathematics Education

To remain competitive in our 21st century global economy, the nation must foster new opportunities, approaches, and technologies in math and science education. This begins with a coordinated effort to bolster science, technology, engineering, and math (S.T.E.M.) education nationwide, starting at the earliest stages in education. Developing a more diverse and academically prepared workforce of individuals in S.T.E.M. disciplines will benefit all aspects of scientific and medical research and care.

NIDA Researchers Discover a New Mechanism Underlying Cocaine Addiction

NIH Research News

Researchers have identified a key epigenetic mechanism in the brain that helps explain cocaine’s addictiveness, according to research funded by the National Institute on Drug Abuse (NIDA), part of the National Institutes of Health.

The study, published in the January issue of the journal Science, shows how cocaine affects an epigenetic process (a process capable of influencing gene expression without changing a gene’s sequence) called histone methylation. These epigenetic changes in the brain’s pleasure circuits, which are also the first impacted by chronic cocaine exposure, likely contribute to an acquired preference for cocaine.