Study Questions Ability of Garlic to Lower LDL Cholesterol

A study published in the Archives of Internal Medicine this week concluded that garlic supplementation does not improve cholesterol profiles in people with moderately high levels of LDL cholesterol (defined here as a fasting plasma LDL cholesterol concentration of 130 to 190 mg/dL, a triglyceride level less than 250 mg/dL and body mass index, calculated as weight in kilograms divided by height in meters squared, of 19 to 30). The study is the first independent, long-term assessment of raw garlic and two popular garlic supplements. Raw garlic (4g/day for 6 months), powdered garlic and aged garlic extract supplement were tested on 192 adults with moderately high levels of LDL cholesterol. None of the garlic forms studied had statistically or clinically significant effects on LDL cholesterol or other plasmid lipid concentrations. The results contradict other recent findings suggesting that garlic may be beneficial in heart health by reducing moderately high levels of LDL cholesterol in adults [1-2].