Oral Immunotherapy Shows Promise as Treatment for Egg Allergy

Giving children and adolescents with egg allergy small but increasing daily doses of egg white powder holds the possibility of developing into a way to enable some of them to eat egg-containing foods without having allergic reactions, according to a study supported by the National Institutes of Health (NIH). The study results will appear online in the July 19th issue of the New England Journal of Medicine [1].

Consortium of Food Allergy Research (CoFAR)

Childhood Cancer Linked to Delays in Developmental Milestones

Infants and toddlers who have been treated for cancer tend to reach certain developmental milestones later than do their healthy peers, say researchers at the National Institutes of Health (NIH) and in Italy. The findings show that delays may occur early in the course of treatment and suggest that young children with cancer might benefit from such early interventions as physical or language therapy.

Child with cancer

Obama Budget Calls for Sustained Investment in Research

In his State of the Union address last month, President Barack Obama reaffirmed the prioritization of science and technology in his plans for the nation’s future. The President’s new economic plan calls for maintaining a commitment to funding research and development that can improve our quality of life.

Obama budget calls for sustained investment in research

Study Identifies Likely Mechanism Underlying Resveratrol Activity

National Institutes of Health researchers and their colleagues have identified how resveratrol, a naturally occurring chemical found in red wine and other plant products, may confer its health benefits. The authors present evidence that resveratrol does not directly activate sirtuin 1, a protein associated with aging. Rather, the authors found that resveratrol inhibits certain types of proteins known as phosphodiesterases (PDEs), enzymes that help regulate cell energy.

These findings may help settle the debate regarding resveratrol’s biochemistry and pave the way for resveratrol-based medicines. The chemical has received significant interest from pharmaceutical companies for its potential to combat diabetes, inflammation, and cancer. The study appears in the February 3rd issue of the journal Cell [1].

Resveratrol

NIH establishes National Center for Advancing Translational Sciences

In a move to re-engineer the process of translating scientific discoveries into new drugs, diagnostics, and devices, the National Institutes of Health has established the National Center for Advancing Translational Sciences (NCATS). The action was made possible by Congress’ approval of a fiscal year 2012 spending bill and the president’s signing of the bill, which includes the establishment of NCATS with a budget of $575 million.

National Center for Advancing Translational Sciences