Genetic Risk Factor for Alzheimer’s Disease Impacts the Blood Brain Barrier

The most common genetic risk factor for Alzheimer’s disease (AD) disrupts the blood brain barrier, impeding oxygen and nutrient flow to the brain and exposing the brain to systemic toxins, according to a recent investigation led by scientists from the University of Rochester Center for Neurodegenerative and Vascular Brain Disorders [1].

Blood brain barrier

Cellular Transport and the Nobel Prize for Medicine

nobel medal in medicine

The 2013 Nobel Prize in Physiology or Medicine was announced yesterday [1]. The prize was awarded to three U.S. scientists for their work on how the cell coordinates its transport system to shuttle proteins and other molecules from one location to another.

The prize of 8-million-Swedish-krona ($1.2-million USD) was divided evenly to Randy W. Schekman, age 65, at the University of California at Berkeley; James E. Rothman, age 63, at Yale University in New Haven, Connecticut; and Thomas C. Südhof, age 58, at Stanford University, for their discoveries of machinery regulating vesicle traffic, a major transport system in cells.

Watermelon Juice Soothes Muscle Pain After Excercise

Watermelon juice is a popular drink among athletes, who have long praised it for replenishing fluids, electrolytes and glucose that get depleted during a workout. A new study identifies an additional benefit: juice from the summer fruit can relieve post-exercise muscle pain [1]. The study is published in the American Chemical Society’s Journal of Agricultural and Food Chemistry.

Watermelon juice

The Incredible, Edible Egg

High cholesterol causes cardiovascular disease. Eggs are high in cholesterol; a large egg contains about 210mg of the stuff, which is concentrated in the yolk. The American Heart Association has recommended that people limit their daily cholesterol consumption to less than 300mg to maintain heart health [1]. Thus, it would seem that we should eat fewer eggs, or at least fewer egg yolks, to prevent cardiovascular disease. Right?


Q&A: What Do My Cholesterol Levels Mean?

Question: I had my cholesterol checked, and I got four numbers back. Which one is most important, and what do the numbers mean with regard to my health?

Focus on cholesterolImage credit: Focus on cholesterol via Shutterstock