By isolating cells from patients’ spinal tissue within a few days after death, researchers funded by the National Institutes of Health have developed a new model of the paralyzing disease amyotrophic lateral sclerosis (ALS). They found that during the disease, cells called astrocytes become toxic to nerve cells — a result previously found in animal models but not in humans. The new model could be used to investigate many more questions about ALS, also known as Lou Gehrig’s disease.

An up-to-date review of the most common neurological disorders in the United States was published in the January 30th issue of Neurology [1]. Researchers reviewed nearly 500 articles published between 1990 and 2005 to determine the rates of prevalence (meaning the total number of cases of a disease in a given population at a specific time; does not convey information about risk) or incidence (meaning the rate of occurrence of new cases of a particular disease in a given population; measures the risk of a disease) for 12 neurological disorders.