According to an international study led by researchers from the Virginia Commonwealth University (VCU) School of Pharmacy, multiple genes contribute to risk for schizophrenia and appear to function in pathways related to transmission of signals in the brain and immunity [1]. The discovery provides scientists with a better understanding the molecular and biological mechanisms involved with schizophrenia that may improve disease management and identify new drug targets. The study is published in the April issue of JAMA Psychiatry.

Could drug addiction treatment of the future be as simple as an on/off switch in the brain? A study in rats has found that stimulating a key part of the brain reduces compulsive cocaine-seeking and suggests the possibility of changing addictive behavior generally [1]. The study, published in the journal Nature, was conducted by scientists at the Intramural Research Program of the National Institute on Drug Abuse (NIDA), part of the National Institutes of Health, and the University of California, San Francisco.

Hearing voices that are not there was once thought to be a core symptom of schizophrenia and signify severe mental illness. It has been increasingly acknowledged that people with no other symptoms of schizophrenia or psychosis do hear voices [1]. There are several theories about what causes these auditory hallucinations. For example, there is good evidence that hearing voices can be linked to trauma [2]. Attempting to understand the phenomenon is not only scientifically interesting but also relates to how society views people with these experiences and if and how they may be treated. A search for how these experiences are associated with brain function is ongoing. New research published in the journal Human Brain Mapping suggests that the predisposition to hearing voices may relate to abnormal functioning of the brain whilst at rest [3].

This week is Brain Awareness Week (BAW), an annual observance dedicated to raising public awareness about the progress and benefits of brain research. Coordinated by the Dana Alliance for Brain Initiatives and the European Dana Alliance for the Brain, every March, BAW unites the efforts of partner organizations around the world in a week-long celebration of the brain.

According to new research, learning becomes more difficult as we get older because our brains get too full for new information. This may be due, in part, to finding that with advanced age we get less sleep during the stage in which we don’t dream. Both studies are reported in the prestigious Nature family of journals.