The most common genetic risk factor for Alzheimer’s disease (AD) disrupts the blood brain barrier, impeding oxygen and nutrient flow to the brain and exposing the brain to systemic toxins, according to a recent investigation led by scientists from the University of Rochester Center for Neurodegenerative and Vascular Brain Disorders .
Researchers from Beth Israel Deaconess Medical Center (BIDMC) report in the October 29th issue of the journal Neurology that elevated levels of the protein alpha-synuclein can be detected in the skin of Parkinson’s disease patients . The finding offers a potential biomarker to enable doctors to identify and diagnose Parkinson’s before the disease has reached an advanced stage.
A good night’s rest may literally clear the mind. Using mice, researchers showed for the first time that the space between brain cells may increase during sleep, allowing the brain to flush out toxins that build up during waking hours. These results suggest a new role for sleep in health and disease. The study was funded by the National Institute of Neurological Disorders and Stroke (NINDS), part of the NIH.