Archives for September 2011

FDA Removing Over-the-counter Asthma Drug From Shelves for Environment

Users of Primatene Mist, the only over-the-counter treatment for acute symptoms of asthma, will need to find an alternative as of December 31, 2011. The U.S. Food and Drug Administration (FDA) recently announced that the medication will no longer be available because it uses chlorofluorocarbons (CFCs) as a propellant agent [1], and CFCs have long been known to deplete Earth’s ozone layer.

Primatine Mist spray

Schizophrenia and Epilepsy May be Linked, Shared Cause Not Yet Known

A recent study published in the journal Epilepsia indicates that there is a bidirectional relationship between schizophrenia and epilepsy [1]. This means that people with schizophrenia are at a higher risk of developing epilepsy, and those with epilepsy face a higher risk of developing schizophrenia. The fact that each disorder acts as a risk factor for the other indicates that the two may share some underlying causative factors, be they genetic, environmental, or neurological in origin.

Schizophrenia and epilepsy

A Step Toward Personalized Asthma Treatment, Gene Variant Linked to Drug Response

Inhaled corticosteroids are used by millions of asthma patients every day. However, as with all treatments to control asthma, there is marked patient-to-patient variability in the response to treatment. New research published today in the New England Journal of Medicine (NEJM) has identified a genetic variant associated with the response to inhaled corticosteroids [1]. Investigators have found that asthma patients who have two copies of a specific gene variant responded only one-third as well to steroid inhalers as those with two copies of the regular gene.

Asthmatic using an inhaler

High-Fructose Corn Syrup Causes More, Faster Weight Gain Than Table Sugar

High-fructose corn syrup, common in processed foods, is more likely than table sugar to increase the rate and amount of weight gain, according to a study in Pharmacology, Biochemistry and Behavior [1]. Specifically, consuming high-fructose corn syrup (HFCS) increases the likelihood of gaining abdominal fat, which is particularly dangerous with regard to risk of heart disease.

High-Fructose Corn Syrup Causes More, Faster Weight Gain Than Table Sugar

Brain Stent Fails to Prevent Strokes, NIH Stroke Prevention Trial has Immediate Implications for Clinical Practice

Patients at a high risk for a second stroke who received intensive medical treatment had fewer strokes and deaths than patients who received a brain stent in addition to the medical treatment, a large nationwide clinical trial has shown. The investigators published the results in the online first edition of the New England Journal of Medicine [1]. The National Institute of Neurological Disorders and Stroke (NINDS), part of the National Institutes of Health, funded the trial. The medical regimen included daily blood-thinning medications and aggressive control of blood pressure and cholesterol.

New enrollment in the study was stopped in April because early data showed significantly more strokes and deaths occurred among the stented patients at the 30-day mark compared to the group who received the medical management alone.

Stent