Archives for May 2009

New Genes Associated with Blood Pressure and Hypertension

May 29, 2009 | by

High blood pressure or hypertension affects more than one in three people worldwide and is a major cause of strokes, heart attacks and heart failure [1]. The degree with which blood pressure traits can be inherited suggests a genetic component. However, limited consistent evidence of genes associated with blood pressure have been produced. A new study in the journal Nature Genetics reports for the first time a number of genes showing significant associations with blood pressure and hypertension across the genome [2].

blood-pressure

Although large-scale genome-wide association studies (GWAS) have been used successfully to identify genes associated with common diseases and traits, studies on blood pressure or hypertension have failed to identify loci at a genome-wide significant threshold (p-value < 5 x 10-8). The significance of GWAS data relies on several variables, including the accuracy of phenotypic measures, density of markers and size of the study population. Thus, if blood pressure variation in the general population is due to multiple genetic factors with small effects, a very large sample size is needed to identify them.

The Spectrum Health Value Study

May 21, 2009 | by

According to a new survey called the Spectrum Health Value Study, when Americans were asked to value their most important health product and/or service as they consider spending their own money, they chose access to care over everything else [1]. Respondents indicated that access to physician services, medical services at a hospital and emergency care services are their most essential and highest valued health priorities.

spectrum-health-value-study

The Institute of Medicine Roundtable on Evidence-Based Medicine brings together leaders from key healthcare sectors to accelerate the collaborative work necessary to drive improvements in the effectiveness and efficiency of medical care. According to a Roundtable issue brief published earlier this year [2]:

While the U.S. has the highest per capita spending on health care of any industrialized nation, health outcomes lag those achieved elsewhere. The increasing costs of care are reducing access to care and constitute an ever heavier burden on employers and consumers. To address both the costs and the performance of the health care system, greater consensus will be required on what constitutes value in health care, and how to measure and increase that value.

Indeed, value is a relative term — what’s valuable to me may not be valuable to you. With policymakers looking to overhaul the U.S. healthcare system, one way to quantify and compare the value of health programs, products and services is to ask consumers and taxpayers.

Healthcare Spending After the Recession

May 12, 2009 | by

Yesterday, the American Medical Association (AMA) and five other major groups representing doctors, hospitals, insurance companies, pharmaceutical companies and union members delivered a letter to President Obama pledging to cut the U.S. growth rate for healthcare spending by 1.5 percent each year from 2010 through 2019 [1]. The coalition’s efforts are intended to supplement upcoming legislation aimed at decreasing healthcare costs for families, businesses and the government.

The savings — an estimated $2 trillion over the next decade — would come from changes in the public-private partnership and include:

  • Administrative standardization, simplification and transparency.
  • Aligning quality and efficiency incentives among providers to reduce over- and under-use of healthcare.
  • Encouraging coordinated care and adherence to evidence-based best practices and therapies.
  • Reducing the cost of doing business by developing technology and regulatory reform.

Although the proposed health expenditure savings is small, experts say it’s significant [2]. The very fact that health industry leaders have stepped forward to voluntarily restrain costs is itself encouraging; these are the same groups that opposed the healthcare reforms proposed by President Clinton in the 1990s.

Put Your Hands Together and Fight the Flu

May 7, 2009 | by

Although the immediate threat of H1N1 — the swine flu — appears to be benign, experts say that the emerging strain could return in a more virulent form in future flu seasons [1]. And with increasing reports of the swine flu close to home, hand washing is more important than ever. Indeed, hand washing is the best way to prevent infection and illness. Some scientists estimate that as much as 80% of all infections are transmitted by unwashed hands [2]. Hand washing is the single most important thing you can do to prevent the spread of infection and to stay healthy. As simple as it may be, there’s a trick to effectively washing your hands with soap and water.

handwashing

Kids learn early on in preschool that to truly prevent the spread of germs, you’ve got to wash your hands. Nevertheless, a dab of soap and a quick rinse isn’t effective. The key is to wash your hands for at least 20 seconds to ensure that you’ve removed the microbes. By rubbing your hands with soapy water, you pull dirt and oil from your skin. The soap lather suspends any germs trapped inside and are then washed away when rinsing.

Cancer Research Blog Carnival #21 – National Cancer Research Month

May 1, 2009 | by

Welcome to the 21st edition of the Cancer Research Blog Carnival, the monthly blog carnival that discusses what’s new in cancer research and includes posts covering cancer biology, cancer genetics, cancer diagnostics and cancer therapeutics. Concomitant with this edition is the start of National Cancer Research Month.

There’s a revolution occurring on the Web: those “authoritative” articles written on traditional, static websites are being replaced with blogs, wikis and online social networks. In the sphere of health, medicine and information technology, this “real-time Web” consists of many who are professionals in the field; their posts are listed below.
In the digital age, these are the characteristics of new media: recent, relevant, reachable and reliable.

In 2007, the United States Congress declared May National Cancer Research Month. The American Association for Cancer Research (AACR) secured resolutions to raise awareness of the critical advances in cancer research made by its 27,000 members and cancer researchers worldwide, and its efforts to ensure a secure future for continued progress against a group of diseases which strike one in every two men and one in every three women.

national-cancer-research-month

Today, ten million cancer survivors are alive in America due to advances in cancer research [1]. National Cancer Research Month reminds us that basic, clinical, epidemiological and behavioral research are essential to identifying causes and developing strategies for cancer prevention, diagnosis, treatment and cures.

With that, let’s find out more about what’s happening in cancer research this month.