NIH-funded researchers were able to eliminate tinnitus in a group of rats by stimulating a nerve in the neck while simultaneously playing a variety of sound tones over an extended period of time, says a study published today in the advance online publication of the journal Nature [1]. The hallmark of tinnitus is often a persistent ringing in the ears that is annoying for some, debilitating for others, and currently incurable. Similar to pressing a reset button in the brain, this new therapy was found to help retrain the part of the brain that interprets sound so that errant neurons reverted back to their original state and the ringing disappeared. The research was conducted by scientists from the University of Texas at Dallas and MicroTransponder Inc., in Dallas.

Francis Collins, Director of the National Institutes of Health (NIH), said last month that he is moving ahead with a plan to create a new center focused on translational medicine, presently called the National Center for the Advancement of Translational Sciences (NCATS) [1]. The strategy comes at a time of mounting frustration from researchers that the abundance of new information about the molecular basis of many diseases hasn’t led to the development of new therapies.

Anxiety caused by stressful events like moving or losing a job is a normal part of life. Anxiety disorders, on the other hand, are characterized by persistent, excessive and disabling fear and worry and get progressively worse if left untreated. It is estimated that anxiety disorders affect between 3 and 14 percent of older adults in a given year. To provide an older audience with additional information, NIHSeniorHealth, the health and wellness website for older adults from the National Institutes of Health (NIH), has added a topic about anxiety disorders.

Visitors to the website can learn about the risk factors, symptoms and treatments for generalized anxiety disorder, social phobia, panic disorder, post-traumatic stress disorder (PTSD), obsessive compulsive disorder (OCD) and specific phobias such as fear of flying or fear of public speaking. Anxiety disorders can severely affect a person’s life, and they are often overlooked in older adults.

Autism Spectrum Disorder (ASD) researchers now can use data from over 10,000 participants enrolled in ASD studies. The National Database for Autism Research (NDAR), created by the National Institutes of Health, recently made the data available. Researchers can now use the NDAR portal to perform queries that simultaneously yield results from multiple datasets. The portal was designed to provide tools to define and standardize data collected by different laboratories under different protocols. It was also built to ensure a collaborative approach and open data access to the whole ASD research community.

Small genetic differences between individuals help explain why some people have a higher risk than others for developing illnesses such as diabetes or cancer. Recently in the journal Nature, the 1000 Genomes Project, an international public-private consortium, published the most comprehensive map of these genetic differences, called variations, estimated to contain approximately 95 percent of the genetic variation of any person on Earth.