Counterfeit ADHD Medication Common On Internet, FDA Warns

While any pharmaceutical purchased online may be counterfeit, of poor quality, or both, the FDA recently warned consumers with specific regard to the prescription drug Adderall, which is used to treat attention deficit hyperactivity disorder (ADHD) [1].

Authentic vs counterfeit Adderall

Mitochondria Dysfunction Occurs Early in Alzheimer’s Disease Prior to Memory Loss, Amyloid Deposits

Mitochondria are specialized subunits inside a cell that produce the cell’s energy and regulate its metabolism. Research suggests that mitochondria may play a central role in neuronal cell survival because they regulate both energy metabolism and cell death pathways. Using genetic mouse models of Alzheimer’s disease, researchers from Mayo Clinic have found that mitochondria in the brain are dysfunctional early in the disease. The findings were recently published in the open access journal PLoS ONE.

Mitochondria

The Synapse from BrainU

From visiting classrooms for Brain Awareness Week, Dr. Janet Dubinsky from the Department of Neuroscience at the University of Minnesota became aware that teachers wanted to learn what neuroscience has uncovered about brain mechanisms of learning and memory. To address this need, the Department of Neuroscience and the Science Museum of Minnesota created BrainU. Her current partner is Dr. Gillian Roerhig from the STEM Education Center.

Launched in 2000, BrainU is a grant-funded professional development program that teaches educators neuroscience principles and effective methodology for teaching neuroscience in the middle to high school classroom. BrainU, the neuroscience teacher institute, provides teachers with up to 160 hours of neuroscience training, materials, and staff support to bring brain science to their students. Participants in these professional workshops receive updates on the latest in neuroscience research — discussion is complemented with hands-on activities and lab work.

The BrainU website provides lesson plans and resources for teachers and some cool stuff, including brain pictures, optical illusions, and movies.

The movie ‘The Synapse’

In the nervous system, the synapse is essential for neuronal function. A synapse is the junction between two nerve cells or neurons, consisting of a minute gap across which impulses pass by diffusion of a neurotransmitter. The movie ‘The Synapse’, used with permission from BrainU, tells an entertaining and informative story of how neurons communicate with each other at synapses, changing information from electrical to chemical and back to electrical signals. Check out their story below (the movie opens in a new window).

The Synapse

Copyright 2000-2012, BrainU, University of Minnesota Department of Neuroscience and Department of Curriculum and Instruction. Supported by a Science Education Partnership Award (SEPA) from the National Center For Research Resources and the Division of Program Coordination, Planning, and Strategic Initiatives of the National Institutes of Health, with additional funding from SEDAPA and ARRA. Its content is solely the responsibility of the authors and does not necessarily represent the official views of NCRR or NIH.

Study Suggests that Alzheimer’s Disease Spreads Through the Brain

Scientists have long debated whether Alzheimer’s disease starts in separate regions of the brain independently and at different times, or if it begins in one region and then spreads. Data from researchers at Columbia University Medical Center supports the latter model, showing that abnormal tau protein — a key feature observed in the brains of patients with Alzheimer’s disease — propagates along anatomically connected networks, between connected and vulnerable neurons. The study was published earlier this month in the online journal PLoS ONE [1].

Neural network in human brainImage credit: Neurons network in human brain via Shutterstock

Building a Circuit Diagram of the Brain

Jennifer Raymond, an associate professor in neurobiology at Stanford University, is building a circuit diagram of the brain. By bridging the gap between individual synapses and whole brain learning and memory, her research is offering new insights and strategies for medical rehabilitation and education.