Genetic Risk Factor for Alzheimer’s Disease Impacts the Blood Brain Barrier

The most common genetic risk factor for Alzheimer’s disease (AD) disrupts the blood brain barrier, impeding oxygen and nutrient flow to the brain and exposing the brain to systemic toxins, according to a recent investigation led by scientists from the University of Rochester Center for Neurodegenerative and Vascular Brain Disorders [1].

Blood brain barrier

2012: Banner Year for New Drugs

Fueled by new cancer therapeutics, last year the annual new molecular and biological entity approval count from the U.S. Food and Drug Administration (FDA) saw its highest year since 1997. One-third of the novel products approved by the FDA’s Center for Drug Evaluation and Research (CDER) are used to treat cancers of the blood, breast, colon, prostate, skin and thyroid.

FDA approved

NIH Researchers Implicate Unique Cell Type in Multiple Sclerosis

Researchers at the National Institutes of Health have found evidence that a unique type of immune cell contributes to multiple sclerosis (MS). Their discovery helps define the effects of one of the newest drugs under investigation for treating MS — daclizumab — and could lead to a new class of drugs for treating MS and other autoimmune disorders.

Neuron

Health Highlights – January 29th, 2010

Health Highlights is a biweekly summary of particularly interesting articles from credible sources of health and medical information that we follow & read. For a complete list of recommeded sources, see our links page.

Health Highlights

Updated Rates of the Most Common Neurological Disorders

An up-to-date review of the most common neurological disorders in the United States was published in the January 30th issue of Neurology [1]. Researchers reviewed nearly 500 articles published between 1990 and 2005 to determine the rates of prevalence (meaning the total number of cases of a disease in a given population at a specific time; does not convey information about risk) or incidence (meaning the rate of occurrence of new cases of a particular disease in a given population; measures the risk of a disease) for 12 neurological disorders.