Mitochondria are specialized subunits inside a cell that produce the cell’s energy and regulate its metabolism. Research suggests that mitochondria may play a central role in neuronal cell survival because they regulate both energy metabolism and cell death pathways. Using genetic mouse models of Alzheimer’s disease, researchers from Mayo Clinic have found that mitochondria in the brain are dysfunctional early in the disease. The findings were recently published in the open access journal PLoS ONE.

When most of us get a massage, we leave in a trance with muscles feeling like jelly. But when Mark Tarnopolsky, Professor of Pediatrics in the Department of Medicine at McMaster University, got a massage — as part of a therapeutic regimen for a hamstring injured while waterskiing — he left determined to figure out exactly what was happening in his muscles at the molecular level to make them feel like jelly. His results are reported in Science Translational Medicine.

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