In a big shift of focus, the personal genomics company 23andMe recently announced the creation of a new therapeutics group with the intention of developing new therapies for both common and rare diseases.
kwiKBio believes it’s taking too long to solve diseases and create cures. The company aims to combine advanced semantic web bioinformatics with contract research organization (CRO) business development in an e-commerce biomedical research portal. Think Wikipedia with an interactive research component coupled with Expedia for purchasing a ticket to a laboratory test.
Last week, the U.S. Department of Health and Human Services (HHS) issued a Notice of Proposed Rulemaking (NPRM), which proposes regulations to implement reporting requirements for clinical trials that are subject to Title VIII (Clinical Trial Databases) of the Food and Drug Administration Amendments Act of 2007 (FDAAA). The proposed rule clarifies requirements to clinical researchers for registering clinical trials and submitting summary trial results information to ClinicalTrials.gov, a publicly accessible database operated by the National Library of Medicine, part of the National Institutes of Health. The NIH also announced a proposal to apply the proposed requirements to all NIH-funded clinical trials, whether subject to FDAAA or not. The proposed policy would require that all NIH-funded clinical trials be registered in ClinicalTrials.gov and that summary results be posted to the database in a timely matter. Both documents are open for a 90-day public comment period, and comments will be taken into consideration before final regulations and a final NIH Policy are issued.
A new research study at Boston Children’s Hospital, in partnership with the Medical College of Wisconsin (MCW) and the Children’s Hospital of Wisconsin Research Institute, is using genetic information to predict children’s reactions to medications. The goal is to enable clinicians to select a more personalized therapy for each patient.
Scientists may have hit the wall when it comes to reading articles. A 35-year trend of researchers reading an increasing number of scholarly manuscripts appears to be leveling off, accompanied by the bottoming out of time taken to read each article.