Brain Stent Fails to Prevent Strokes, NIH Stroke Prevention Trial has Immediate Implications for Clinical Practice

Patients at a high risk for a second stroke who received intensive medical treatment had fewer strokes and deaths than patients who received a brain stent in addition to the medical treatment, a large nationwide clinical trial has shown. The investigators published the results in the online first edition of the New England Journal of Medicine [1]. The National Institute of Neurological Disorders and Stroke (NINDS), part of the National Institutes of Health, funded the trial. The medical regimen included daily blood-thinning medications and aggressive control of blood pressure and cholesterol.

New enrollment in the study was stopped in April because early data showed significantly more strokes and deaths occurred among the stented patients at the 30-day mark compared to the group who received the medical management alone.


Scientists Learn Why a Little Alcohol Can Be Good For You

A number of studies have asserted that moderate drinking has a positive benefit on cardiovascular health. Now, scientists at the University of Rochester Medical Center have discovered how alcohol consumption can help to prevent heart disease. The research, published in the journal Arteriosclerosis, Thrombosis and Vascular Biology, studied the effects of moderate amounts of alcohol in human coronary artery smooth muscle cells and in the carotid arteries of mice [1]. In both cases, regular, limited amounts of alcohol inhibited a protein called Notch 1 and prevented the buildup of smooth muscle cells in blood vessels that leads to the narrowing of the arteries and can put you at risk for a heart attack or stroke.

Red wine

Chiropractic Adjustments and Artery Dissection: Is Your Neck in Safe Hands?

Cervicocerebral arterial dissections are increasingly recognized as a cause of stroke, particularly in young people. The term “cervicocerebral arterial” refers to the arteries in the neck and brain, while the term “dissection” refers to a tear in the inner wall of a major artery. An arterial dissection leads to the intrusion of blood within the layers of the artery wall. Depending upon which layers blood collects, an arterial dissection can cause narrowing of the channel within the artery (termed stenosis), which restricts blood flow, or an aneurysmal dilation, meaning a localized, blood-filled bulge in the artery wall.