About the Author

Robert Martone is a scientist at St. Jude Children's Research Hospital focused on neuro-oncology biomarker research.

Genetic Risk Factor for Alzheimer’s Disease Impacts the Blood Brain Barrier

The most common genetic risk factor for Alzheimer’s disease (AD) disrupts the blood brain barrier, impeding oxygen and nutrient flow to the brain and exposing the brain to systemic toxins, according to a recent investigation led by scientists from the University of Rochester Center for Neurodegenerative and Vascular Brain Disorders [1].

Blood brain barrier

Pain and the Prognosis for Dementia

While researchers are busy developing sophisticated laboratory tests to predict who will eventually succumb to Alzheimer’s disease, a seemingly mundane observation may provide one of the strongest predictors yet identified: pain.

Pharmacology of aging why age matters